Arrow info Don’t forget to complete your doctor discussion guide here! Close
Prescription icon

Savings and support

Personalized support. That helps.

Patient portrayal.

Sign up

All fields are required unless otherwise stated


Are you under the age of 18, are you covered by Medicare, Medicaid, or any other government insurance, or are you a cash paying patient? (FEHB is not included for purposes of this offer.)

You are eligible for the tAccess program, including the Savings Card

Remember you can get tips and advice, and inspirational messages when you sign up for tAccess.

You are not eligible for a Savings Card, but you can still sign up for tAccess for support if you are age 18 or older

Remember you can get tips and advice, and inspirational messages when you sign up for tAccess.


Enter your information

Please select the statement that best describes you:

Text messages:

By agreeing to these tAccess Support Program (“Program”) SMS terms and conditions, you agree to receive text messages on your mobile device subject to the Terms & Conditions described below. You understand that this consent is not a condition of purchase or use of TRINTELLIX or of any Takeda product or service.

  • Participants will receive an average of ten or more text messages each month while enrolled in the Program
  • There is no fee payable to Takeda to receive text messages, however, your carrier’s message and data rates may apply
  • Data obtained from you in connection with your registration for, and use of, this SMS service may include your phone number and/or email address, related carrier information, and elements of pharmacy claim information and will be used to administer this Program and to provide Program benefits such as information about your prescription, refill reminders, as well as Program updates and alerts
  • Takeda will not be liable for any delays in the receipt of any SMS messages as delivery is subject to effective transmission from your network operator 
  • The Program is valid with most major US carriers, including: Verizon Wireless, Sprint, Nextel, Boost, T-Mobile®, AT&T, Alltel, ACS Wireless, Bluegrass Cellular, Carolina West Wireless, CellCom, Cellular One of East Central Illinois (ECIT), Cincinnati Bell, Cricket, C-Spire Wireless, Duet IP (AKA Max/Benton/Albany), Element Mobile, Epic Touch, GCI Communications, Golden State, Hawkeye (Chat Mobility), Hawkeye (NW Missouri Cellular), Illinois Valley Cellular (IVC), Inland Cellular, iWireless, Keystone Wireless (Immix/PC Management), MetroPCS, MobiPCS, Mosaic, MTPCS/Cellular One (Cellone Nation), Nex-Tech Wireless, nTelos, Panhandle Telecommunications, Pioneer, Plateau, Revol Wireless, Rina-Custer, Rina-Silver Star, Rina-South Central Comm, Rina-Syringa, Rina-UBET, Rina-Manti, Simmetry, South Canaan/CellularOne of NEPA, Thumb Cellular, Union Wireless, United Wireless, U.S. Cellular, Viaero Wireless, Virgin Mobile, West Central Wireless (includes Five Star Wireless)
  • Takeda may be required to contact the user if an adverse event is reported
  • Takeda reserves the right to rescind, revoke, or amend the tAccess Support Program without notice at any time
  • While Takeda makes reasonable efforts to include accurate, up-to-date information for this Program, Takeda makes no representations or warranties as to its accuracy. Takeda assumes no liability for any errors or omissions in the information communicated through this Program, and it is not intended to make a diagnosis or take the place of talking to a U.S. healthcare professional.
  • You can unsubscribe from the Program by texting STOP. For questions about this Program, text HELP or contact the customer support center at 1-866-279-0287
Sorry we couldn’t complete your registration at this time. Please contact 1-866-279-0287 to speak to a live agent who will be able to assist you. Sorry we couldn’t complete your registration at this time. It looks like you already have a card that is activated. Please contact 1-866-279-0287 to speak to a live agent who will be able to assist you. There was a problem with your SMS registration. Your SMS confirmation response may be delayed.
Help At Hand: Patient Assistance Within Reach

Need help affording your prescription?

Visit Takeda Help At Hand to learn more.

Mail-in rebate

Patient mail-in rebate forms and information on eligibility and how to complete and submit are available at
You may also request one by calling 1-866-279-0287.

Frequently asked questions

  • If eligible, you can register for the TRINTELLIX Savings Card here. If you are having trouble signing up online or have questions about eligibility requirements, you can also call 1-866-279-0287 to register.

  • The TRINTELLIX Savings Card offer cannot be used if you are a beneficiary of, or any part of your prescription is covered by: (1) any federal, state, or government-funded healthcare program (for example, Medicare, Medicaid, TRICARE), including a state pharmaceutical assistance program (the Federal Employees Health Benefits (FEHB) Program is not a government-funded healthcare program for purposes of this offer), (2) the Medicare Prescription Drug Program (Part D), or if you are currently in the coverage gap, or (3) insurance that is paying the entire cost of the prescription. Patient must be age 18 or older and have a valid prescription for TRINTELLIX. Cash patients are not eligible for the TRINTELLIX Savings Card.

  • If you’re an eligible patient signing up for a TRINTELLIX Savings Card online, you will receive your activated card online immediately. You can print the Savings Card and use it right away. If you’re having trouble activating your Savings Card online, please call 1-866-279-0287 to activate it.

    If you received a TRINTELLIX Savings Card from your healthcare professional in the brochure, you can activate it here, or call 1-866-279-0287. You will be asked for the ID number on the card.

    Once you’ve activated your TRINTELLIX Savings Card, take your prescription and your savings card to your pharmacist.*

    *Must meet eligibility requirements, and subject to a maximum savings amount of $100 per 30-day or $300 per 90-day prescription. See savings card for Eligibility Requirements and Terms & Conditions.

  • With the TRINTELLIX Savings Card, eligible patients can save on TRINTELLIX prescriptions and refills. You also get free access to the TRINTELLIX Support Program, tAccess, which provides support for people with MDD.

    See "Am I eligible for the TRINTELLIX Savings Card?" above.

  • The tAccess Support Program is personalized support for patients on TRINTELLIX therapy. The purpose of the program is to help patients stay on track with their treatment as directed by their healthcare professional.

    Patients who enroll in the tAccess Support Program can expect to receive:

    • Savings Card* - pay as little as $10 for a 30- or 90-day prescription. Maximum savings of $100 on a 30-day or $300 on a 90-day script. Must meet eligibility requirements.
    • Mobile Wallet* - download your Savings Card and add it to your mobile wallet for your next refill. Must meet eligibility requirements.
    • Informative emails - Receive emails with tools to help empower you to have meaningful discussions with your doctor.
    • Inspiring texts and refill reminders when needed - Helpful messages and medication refill reminders sent to help you along the way.
    • Chats with a tAccess advisor - Call to receive information about the Savings Card and other support features (1-844-654-TRIN), 8:00 am – 8:00 pm EST M-F.

    *All TRINTELLIX patients can join the tAccess Support Program. Only commercially insured patients are eligible for the TRINTELLIX Savings Card. The TRINTELLIX Savings Card cannot be used by patients in federal, state, or government-funded healthcare programs or by cash patients. See Savings Card for Eligibility Requirements and Terms & Conditions.

  • If the pharmacy has difficulty processing your card, have the pharmacy follow the steps on the back of your TRINTELLIX Savings Card. The pharmacy can also call 1-866-279-0287 for processing questions.

    If eligible and your pharmacist cannot process your card, or doesn’t accept your card and you’ve already paid for your prescription, please visit and follow the instructions for savings. If you need further information, call 1-866-279-0287.

  • Patient mail-in rebate forms for eligible patients and information on how to complete and submit them are available at You may also request one by calling 1-866-279-0287.

  • For general information about TRINTELLIX Savings Cards, including information for getting a replacement card, call 1-866-279-0287.

  • Help At Hand is a patient assistance program that provides access to medicine for eligible patients with financial need. Visit Help At Hand to request an application. Restrictions apply.



Suicidal Thoughts & Actions

TRINTELLIX and other antidepressants may increase suicidal thoughts and actions in some people 24 years of age and younger, especially within the first few months of treatment or when the dose is changed. TRINTELLIX is not for use in children under 18. Depression or other mental illnesses are the most important causes of suicidal thoughts or actions. Pay close attention to any changes, especially new or sudden changes in mood, behavior, thoughts, or feelings. Call your doctor or get emergency help right away if you have symptoms such as suicidal thoughts or actions, impulsivity, aggressive or violent actions, depression, anxiety or panic attacks, agitation, restlessness, anger, irritability, trouble sleeping, an increase in activity or talking, or other unusual changes in behavior or mood; especially if they are new, worse, or worry you.

Who should not take TRINTELLIX?

Do not start or take TRINTELLIX if you:

  • are allergic to vortioxetine or any of the ingredients in TRINTELLIX
  • take a Monoamine Oxidase Inhibitor (MAOI)
  • have stopped taking an MAOI in the last 14 days
  • are being treated with the antibiotic linezolid or intravenous methylene blue

Do not start taking an MAOI for at least 21 days after you stop treatment with TRINTELLIX.

What should I tell my doctor before taking TRINTELLIX?

Before taking TRINTELLIX, tell your doctor:

  • about all your medical and other health conditions
  • if you are pregnant or plan to become pregnant, since TRINTELLIX may harm your unborn baby. Taking TRINTELLIX during your third trimester may cause your baby to have withdrawal symptoms after birth or to be at increased risk for a serious lung problem at birth. Tell your doctor right away if you become or think you are pregnant while taking TRINTELLIX.
  • if you are breastfeeding or plan to breastfeed, since it is not known if TRINTELLIX passes into your breast milk

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements, since TRINTELLIX and some medicines may cause serious side effects (or may not work as well) when taken together. Especially tell your doctor if you take: medicines for migraine headache called triptans; tricyclic antidepressants; opioids (such as fentanyl and tramadol); lithium; tryptophan; buspirone; St. John’s Wort; medicines that can affect blood clotting such as aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin; and diuretics.

What are the possible side effects of TRINTELLIX?

TRINTELLIX may cause serious side effects, including:

  • Serotonin syndrome: A potentially life‐threatening problem that can happen when you take TRINTELLIX with certain other medicines. Call your doctor or go to the nearest emergency room right away if you have any of the following signs and symptoms of serotonin syndrome: agitation; seeing or hearing things that are not real; confusion; coma; fast heart beat; changes in blood pressure; dizziness; sweating; flushing; high body temperature; shaking, stiff muscles, or muscle twitching; loss of coordination; seizures; nausea, vomiting, diarrhea.
  • Increased risk of bleeding: Taking TRINTELLIX with aspirin, NSAIDs, warfarin or blood thinners may add to this risk. Tell your doctor right away about any unusual bleeding or bruising.
  • Manic episodes: Manic episodes may happen in people with bipolar disorder who take TRINTELLIX. Symptoms may include: greatly increased energy; racing thoughts; unusually grand ideas; talking more or faster than usual; severe problems sleeping; reckless behavior; excessive happiness or irritability.
  • Discontinuation syndrome: Suddenly stopping TRINTELLIX may cause you to have serious side effects including: nausea; sweating; changes in your mood; irritability and agitation; dizziness; electric shock feeling; tremor; anxiety; confusion; headache; tiredness; problems sleeping; hypomania; ringing in your ears; seizures.
  • Eye problems: TRINTELLIX may cause a type of eye problem called angle-closure glaucoma in people with certain other eye conditions. You may want to undergo an eye examination to see if you are at risk and receive preventative treatment if you are. Call your doctor if you have eye pain, changes in your vision, or swelling or redness in or around the eye.
  • Low levels of salt (sodium) in your blood: Low sodium levels in your blood that may be serious and may cause death can happen during treatment with TRINTELLIX. Elderly people and people who take certain medicines may be at a greater risk for developing low sodium levels in your blood. Signs and symptoms may include headache; difficulty concentrating; memory changes; confusion; weakness and unsteadiness on your feet which can lead to falls. In more severe or more sudden cases, signs and symptoms include: seeing or hearing things that are not real; fainting; seizures; coma; stopping breathing.
  • Sexual problems: Taking antidepressants like TRINTELLIX may cause sexual problems. Symptoms in males may include: delayed ejaculation or inability to have an ejaculation, decreased sex drive, or problems getting or keeping an erection. Symptoms in females may include: decreased sex drive, or delayed orgasm or inability to have an orgasm. Talk to your healthcare provider if you develop any changes in your sexual function or if you have any questions or concerns about sexual problems during treatment with TRINTELLIX.

The most common side effects of TRINTELLIX include:

  • nausea
  • constipation
  • vomiting

These are not all the possible side effects of TRINTELLIX. Tell your doctor if you have any side effect that bothers you or does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

What is TRINTELLIX (vortioxetine)?

TRINTELLIX is a prescription medicine used in adults to treat a certain type of depression called Major Depressive Disorder (MDD).

There is a pregnancy registry for females who are exposed to antidepressants during pregnancy. The purpose of the registry is to collect information about the health of females exposed to antidepressants and their babies. If you become pregnant during treatment with TRINTELLIX, talk to your healthcare provider about registering with the National Pregnancy Registry for Antidepressants at 1-844-405-6185 or visiting online at

For additional Important Safety Information, click here for Medication Guide, and discuss with your doctor.